Our publications
Showing our recent 25 publications from our lab and collaborations with other labs.
Click here to see all our lab's publications on PubMed.
(last updated 2020.04.27)
Click here to see all our lab's publications on PubMed.
(last updated 2020.04.27)
High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange.
Overall SA, Toor JS, Hao S, Yarmarkovich M, Sara M O'Rourke, Morozov GI, Nguyen S, Japp AS, Gonzalez N, Moschidi D, Betts MR, Maris JM, Smibert P, Sgourakis NG.Nat Commun. 2020 Apr 20;11(1):1909. doi: 10.1038/s41467-020-15710-1.
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8(+) T cells
Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, Naji A, Reyes-Terán G, Estes JD, Price DA, Douek DC, Deeks SG, Buggert M, Betts MR.
Sci Transl Med. 2019 Dec 18;11(523). pii: eaax4077. doi: 10.1126/scitranslmed.aax4077.
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease
Fajgenbaum DC, Langan RA, Japp AS, Partridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, Jordan MB, Cohen AD, Krymskaya V, Rubenstein A, Betts MR, Kambayashi T, van Rhee F, Uldrick TS.
J Clin Invest. 2019 Aug 13;130(10):4451-4463. doi: 10.1172/JCI126091.
Human CD4(+)CD103(+) cutaneous resident memory T cells are found in the circulation of healthy individuals
Klicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK.
Sci Immunol. 2019 Jul 5;4(37). pii: eaav8995. doi: 10.1126/sciimmunol.aav8995.
T follicular helper cells in human efferent lymph retain lymphoid characteristics
Vella LA, Buggert M, Manne S, Herati RS, Sayin I, Kuri-Cervantes L, Bukh Brody I, O'Boyle KC, Kaprielian H, Giles JR, Nguyen S, Muselman A, Antel JP, Bar-Or A, Johnson ME, Canaday DH, Naji A, Ganusov VV, Laufer TM, Wells AD, Dori Y, Itkin MG, Betts MR, Wherry EJ.
J Clin Invest. 2019 Jul 2;129(8):3185-3200. doi: 10.1172/JCI125628. eCollection 2019 Jul 2.
Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B
Chang KM, Traum D, Park JJ, Ho S, Ojiro K, Wong DK, Wahed AS, Terrault NA, Khalili M, Sterling RK, Janssen HLA, Shuhart MC, Lau DT, Roberts LR, Johnson GS, Kaplan DE, Betts MR, Lee WM, Lok ASF; Hepatitis B Research Network (HBRN).
PLoS Pathog. 2019 Apr 18;15(4):e1007715. doi: 10.1371/journal.ppat.1007715. eCollection 2019 Apr.
Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model
Brody IB, Calcedo R, Connell MJ, Carnathan DG, Nason M, Lawson BO, Nega MT, Boyd S, Qin Q, Vanderford TH, Wilson JM, Wilson JM, Silvestri G, Betts MR.
Pathog Immun. 2019 Jan 29;4(1):1-20. doi: 10.20411/pai.v4i1.241. eCollection 2019.
AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver
Greig JA, Calcedo R, Kuri-Cervantes L, Nordin JML, Albrecht J, Bote E, Goode T, Chroscinski EA, Bell P, Richman LK, Betts MR, Wilson JM.
Mol Ther Methods Clin Dev. 2018 Dec 5;11:191-201. doi: 10.1016/j.omtm.2018.10.012. eCollection 2018 Dec 14.
Everything in its right place: resident memory CD8+ T cell immunosurveillance of HIV infection
Buggert M, Japp AS, Betts MR.
Curr Opin HIV AIDS. 2019 Mar;14(2):93-99. doi: 10.1097/COH.0000000000000523.
The CD4(-)CD8(-) MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8(+) MAIT cell pool
Dias J, Boulouis C, Gorin JB, van den Biggelaar RHGA, Lal KG, Gibbs A, Loh L, Gulam MY, Sia WR, Bari S, Hwang WYK, Nixon DF, Nguyen S, Betts MR, Buggert M, Eller MA, Broliden K, Tjernlund A, Sandberg JK, Leeansyah E.
Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11513-E11522. doi: 10.1073/pnas.1812273115. Epub 2018 Nov 15.
Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue
Steblyanko M, Anikeeva N, Buggert M, Betts MR, Sykulev Y.
J Vis Exp. 2018 Jul 30;(137):58143. doi: 10.3791/58143.
Identification and characterization of HIV-specific resident memory CD8(+) T cells in human lymphoid tissue
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.
Sci Immunol. 2018 Jun 1;3(24):eaar4526. doi: 10.1126/sciimmunol.aar4526.
Spatial distribution and function of T follicular regulatory cells in human lymph nodes
Sayin I, Radtke AJ, Vella LA, Jin W, Wherry EJ, Buggert M, Betts MR, Herati RS, Germain RN, Canaday DH.
J Exp Med. 2018 Jun 4;215(6):1531-1542. doi: 10.1084/jem.20171940. Epub 2018 May 16.
CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells
Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ.
Sci Transl Med. 2018 Apr 18;10(437):eaar6759. doi: 10.1126/scitranslmed.aar6759.
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease
Buggert M, Nguyen S, McLane LM, Steblyanko M, Anikeeva N, Paquin-Proulx D, Del Rio Estrada PM, Ablanedo-Terrazas Y, Noyan K, Reuter MA, Demers K, Sandberg JK, Eller MA, Streeck H, Jansson M, Nowak P, Sönnerborg A, Canaday DH, Naji A, Wherry EJ, Robb ML, Deeks SG, Reyes-Teran G, Sykulev Y, Karlsson AC, Betts MR.
PLoS Pathog. 2018 Apr 13;14(4):e1006973. doi: 10.1371/journal.ppat.1006973. eCollection 2018 Apr.
The receptor repertoire and functional profile of follicular T cells in HIV-infected lymph nodes
Wendel BS, Del Alcazar D, He C, Del Río-Estrada PM, Aiamkitsumrit B, Ablanedo-Terrazas Y, Hernandez SM, Ma KY, Betts MR, Pulido L, Huang J, Gimotty PA, Reyes-Terán G, Jiang N, Su LF.
Sci Immunol. 2018 Apr 6;3(22):eaan8884. doi: 10.1126/sciimmunol.aan8884.
Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions
Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M.
JCI Insight. 2018 Apr 5;3(7):e98487. doi: 10.1172/jci.insight.98487. eCollection 2018 Apr 5.
Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells
Noyan K, Nguyen S, Betts MR, Sönnerborg A, Buggert M.
Front Immunol. 2018 Jan 22;9:19. doi: 10.3389/fimmu.2018.00019. eCollection 2018.
HIV-Specific CD8(+) T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue
Reuter MA, Del Rio Estrada PM, Buggert M, Petrovas C, Ferrando-Martinez S, Nguyen S, Sada Japp A, Ablanedo-Terrazas Y, Rivero-Arrieta A, Kuri-Cervantes L, Gunzelman HM, Gostick E, Price DA, Koup RA, Naji A, Canaday DH, Reyes-Terán G, Betts MR.
Cell Rep. 2017 Dec 19;21(12):3458-3470. doi: 10.1016/j.celrep.2017.11.075.
T-bet-expressing B cells during HIV and HCV infections
Knox JJ, Kaplan DE, Betts MR.
Cell Immunol. 2017 Nov;321:26-34. doi: 10.1016/j.cellimm.2017.04.012. Epub 2017 Jul 11.
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response
Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR.
JCI Insight. 2017 Apr 20;2(8):e92943. doi: 10.1172/jci.insight.92943. eCollection 2017 Apr 20.
Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency
Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM.
Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1655-1659. doi: 10.1073/pnas.1617726114. Epub 2017 Jan 30.
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies
Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, Ruiz-Mateos E, Vagios I, Leal M, Ablanedo-Terrazas Y, Rivero A, Gonzalez-Hernandez LA, McDermott AB, Moir S, Reyes-Terán G, Docobo F, Pantaleo G, Douek DC, Betts MR, Estes JD, Germain RN, Mascola JR, Koup RA.
Sci Transl Med. 2017 Jan 18;9(373):eaag2285. doi: 10.1126/scitranslmed.aag2285.
Perturbed CD8(+) T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC.
Sci Rep. 2017 Jan 13;7:40354. doi: 10.1038/srep40354.
Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques
Roberts ER, Carnathan DG, Li H, Shaw GM, Silvestri G, Betts MR.
PLoS Pathog. 2016 Dec 30;12(12):e1006135. doi: 10.1371/journal.ppat.1006135. eCollection 2016 Dec.
CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection
Buggert M, Frederiksen J, Lund O, Betts MR, Biague A, Nielsen M, Tauriainen J, Norrgren H, Medstrand P, Karlsson AC, Jansson M; SWEGUB CORE group.
AIDS. 2016 Oct 23;30(16):2415-2426. doi: 10.1097/QAD.0000000000001223.
Overall SA, Toor JS, Hao S, Yarmarkovich M, Sara M O'Rourke, Morozov GI, Nguyen S, Japp AS, Gonzalez N, Moschidi D, Betts MR, Maris JM, Smibert P, Sgourakis NG.Nat Commun. 2020 Apr 20;11(1):1909. doi: 10.1038/s41467-020-15710-1.
Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8(+) T cells
Nguyen S, Deleage C, Darko S, Ransier A, Truong DP, Agarwal D, Japp AS, Wu VH, Kuri-Cervantes L, Abdel-Mohsen M, Del Rio Estrada PM, Ablanedo-Terrazas Y, Gostick E, Hoxie JA, Zhang NR, Naji A, Reyes-Terán G, Estes JD, Price DA, Douek DC, Deeks SG, Buggert M, Betts MR.
Sci Transl Med. 2019 Dec 18;11(523). pii: eaax4077. doi: 10.1126/scitranslmed.aax4077.
Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease
Fajgenbaum DC, Langan RA, Japp AS, Partridge HL, Pierson SK, Singh A, Arenas DJ, Ruth JR, Nabel CS, Stone K, Okumura M, Schwarer A, Jose FF, Hamerschlak N, Wertheim GB, Jordan MB, Cohen AD, Krymskaya V, Rubenstein A, Betts MR, Kambayashi T, van Rhee F, Uldrick TS.
J Clin Invest. 2019 Aug 13;130(10):4451-4463. doi: 10.1172/JCI126091.
Human CD4(+)CD103(+) cutaneous resident memory T cells are found in the circulation of healthy individuals
Klicznik MM, Morawski PA, Höllbacher B, Varkhande SR, Motley SJ, Kuri-Cervantes L, Goodwin E, Rosenblum MD, Long SA, Brachtl G, Duhen T, Betts MR, Campbell DJ, Gratz IK.
Sci Immunol. 2019 Jul 5;4(37). pii: eaav8995. doi: 10.1126/sciimmunol.aav8995.
T follicular helper cells in human efferent lymph retain lymphoid characteristics
Vella LA, Buggert M, Manne S, Herati RS, Sayin I, Kuri-Cervantes L, Bukh Brody I, O'Boyle KC, Kaprielian H, Giles JR, Nguyen S, Muselman A, Antel JP, Bar-Or A, Johnson ME, Canaday DH, Naji A, Ganusov VV, Laufer TM, Wells AD, Dori Y, Itkin MG, Betts MR, Wherry EJ.
J Clin Invest. 2019 Jul 2;129(8):3185-3200. doi: 10.1172/JCI125628. eCollection 2019 Jul 2.
Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B
Chang KM, Traum D, Park JJ, Ho S, Ojiro K, Wong DK, Wahed AS, Terrault NA, Khalili M, Sterling RK, Janssen HLA, Shuhart MC, Lau DT, Roberts LR, Johnson GS, Kaplan DE, Betts MR, Lee WM, Lok ASF; Hepatitis B Research Network (HBRN).
PLoS Pathog. 2019 Apr 18;15(4):e1007715. doi: 10.1371/journal.ppat.1007715. eCollection 2019 Apr.
Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model
Brody IB, Calcedo R, Connell MJ, Carnathan DG, Nason M, Lawson BO, Nega MT, Boyd S, Qin Q, Vanderford TH, Wilson JM, Wilson JM, Silvestri G, Betts MR.
Pathog Immun. 2019 Jan 29;4(1):1-20. doi: 10.20411/pai.v4i1.241. eCollection 2019.
AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver
Greig JA, Calcedo R, Kuri-Cervantes L, Nordin JML, Albrecht J, Bote E, Goode T, Chroscinski EA, Bell P, Richman LK, Betts MR, Wilson JM.
Mol Ther Methods Clin Dev. 2018 Dec 5;11:191-201. doi: 10.1016/j.omtm.2018.10.012. eCollection 2018 Dec 14.
Everything in its right place: resident memory CD8+ T cell immunosurveillance of HIV infection
Buggert M, Japp AS, Betts MR.
Curr Opin HIV AIDS. 2019 Mar;14(2):93-99. doi: 10.1097/COH.0000000000000523.
The CD4(-)CD8(-) MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8(+) MAIT cell pool
Dias J, Boulouis C, Gorin JB, van den Biggelaar RHGA, Lal KG, Gibbs A, Loh L, Gulam MY, Sia WR, Bari S, Hwang WYK, Nixon DF, Nguyen S, Betts MR, Buggert M, Eller MA, Broliden K, Tjernlund A, Sandberg JK, Leeansyah E.
Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11513-E11522. doi: 10.1073/pnas.1812273115. Epub 2018 Nov 15.
Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue
Steblyanko M, Anikeeva N, Buggert M, Betts MR, Sykulev Y.
J Vis Exp. 2018 Jul 30;(137):58143. doi: 10.3791/58143.
Identification and characterization of HIV-specific resident memory CD8(+) T cells in human lymphoid tissue
Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR.
Sci Immunol. 2018 Jun 1;3(24):eaar4526. doi: 10.1126/sciimmunol.aar4526.
Spatial distribution and function of T follicular regulatory cells in human lymph nodes
Sayin I, Radtke AJ, Vella LA, Jin W, Wherry EJ, Buggert M, Betts MR, Herati RS, Germain RN, Canaday DH.
J Exp Med. 2018 Jun 4;215(6):1531-1542. doi: 10.1084/jem.20171940. Epub 2018 May 16.
CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells
Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ.
Sci Transl Med. 2018 Apr 18;10(437):eaar6759. doi: 10.1126/scitranslmed.aar6759.
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease
Buggert M, Nguyen S, McLane LM, Steblyanko M, Anikeeva N, Paquin-Proulx D, Del Rio Estrada PM, Ablanedo-Terrazas Y, Noyan K, Reuter MA, Demers K, Sandberg JK, Eller MA, Streeck H, Jansson M, Nowak P, Sönnerborg A, Canaday DH, Naji A, Wherry EJ, Robb ML, Deeks SG, Reyes-Teran G, Sykulev Y, Karlsson AC, Betts MR.
PLoS Pathog. 2018 Apr 13;14(4):e1006973. doi: 10.1371/journal.ppat.1006973. eCollection 2018 Apr.
The receptor repertoire and functional profile of follicular T cells in HIV-infected lymph nodes
Wendel BS, Del Alcazar D, He C, Del Río-Estrada PM, Aiamkitsumrit B, Ablanedo-Terrazas Y, Hernandez SM, Ma KY, Betts MR, Pulido L, Huang J, Gimotty PA, Reyes-Terán G, Jiang N, Su LF.
Sci Immunol. 2018 Apr 6;3(22):eaan8884. doi: 10.1126/sciimmunol.aan8884.
Human MAIT cells exit peripheral tissues and recirculate via lymph in steady state conditions
Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M.
JCI Insight. 2018 Apr 5;3(7):e98487. doi: 10.1172/jci.insight.98487. eCollection 2018 Apr 5.
Human Immunodeficiency Virus Type-1 Elite Controllers Maintain Low Co-Expression of Inhibitory Receptors on CD4+ T Cells
Noyan K, Nguyen S, Betts MR, Sönnerborg A, Buggert M.
Front Immunol. 2018 Jan 22;9:19. doi: 10.3389/fimmu.2018.00019. eCollection 2018.
HIV-Specific CD8(+) T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue
Reuter MA, Del Rio Estrada PM, Buggert M, Petrovas C, Ferrando-Martinez S, Nguyen S, Sada Japp A, Ablanedo-Terrazas Y, Rivero-Arrieta A, Kuri-Cervantes L, Gunzelman HM, Gostick E, Price DA, Koup RA, Naji A, Canaday DH, Reyes-Terán G, Betts MR.
Cell Rep. 2017 Dec 19;21(12):3458-3470. doi: 10.1016/j.celrep.2017.11.075.
T-bet-expressing B cells during HIV and HCV infections
Knox JJ, Kaplan DE, Betts MR.
Cell Immunol. 2017 Nov;321:26-34. doi: 10.1016/j.cellimm.2017.04.012. Epub 2017 Jul 11.
T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response
Knox JJ, Buggert M, Kardava L, Seaton KE, Eller MA, Canaday DH, Robb ML, Ostrowski MA, Deeks SG, Slifka MK, Tomaras GD, Moir S, Moody MA, Betts MR.
JCI Insight. 2017 Apr 20;2(8):e92943. doi: 10.1172/jci.insight.92943. eCollection 2017 Apr 20.
Class I-restricted T-cell responses to a polymorphic peptide in a gene therapy clinical trial for α-1-antitrypsin deficiency
Calcedo R, Somanathan S, Qin Q, Betts MR, Rech AJ, Vonderheide RH, Mueller C, Flotte TR, Wilson JM.
Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1655-1659. doi: 10.1073/pnas.1617726114. Epub 2017 Jan 30.
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies
Petrovas C, Ferrando-Martinez S, Gerner MY, Casazza JP, Pegu A, Deleage C, Cooper A, Hataye J, Andrews S, Ambrozak D, Del Río Estrada PM, Boritz E, Paris R, Moysi E, Boswell KL, Ruiz-Mateos E, Vagios I, Leal M, Ablanedo-Terrazas Y, Rivero A, Gonzalez-Hernandez LA, McDermott AB, Moir S, Reyes-Terán G, Docobo F, Pantaleo G, Douek DC, Betts MR, Estes JD, Germain RN, Mascola JR, Koup RA.
Sci Transl Med. 2017 Jan 18;9(373):eaag2285. doi: 10.1126/scitranslmed.aag2285.
Perturbed CD8(+) T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC.
Sci Rep. 2017 Jan 13;7:40354. doi: 10.1038/srep40354.
Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques
Roberts ER, Carnathan DG, Li H, Shaw GM, Silvestri G, Betts MR.
PLoS Pathog. 2016 Dec 30;12(12):e1006135. doi: 10.1371/journal.ppat.1006135. eCollection 2016 Dec.
CD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection
Buggert M, Frederiksen J, Lund O, Betts MR, Biague A, Nielsen M, Tauriainen J, Norrgren H, Medstrand P, Karlsson AC, Jansson M; SWEGUB CORE group.
AIDS. 2016 Oct 23;30(16):2415-2426. doi: 10.1097/QAD.0000000000001223.